Analysis of the hydroxychloroquine dosing regimen in RECOVERY and SOLIDARITY

Pharmacokinetic modeling in combination with information regarding blood levels and mortality from a case series involving 302 patients with chloroquine overdose predicts that a chloroquine regimen that was equivalent to the hydroxychloroquine regimen used in our trial should have an acceptable safety profile

From Tett et al., 1989
Raw data and calculation here
Raw data and calculations

“There was a small absolute excess of cardiac mortality of 0.4 percentage points in the hydroxychloroquine group on the basis of very few events”

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